This is an idea which the wife and I worked on.
I chose 4 different realms in regards to picking the Horsemen.
Death - Comic Book Realm/DC - Doomsday. I felt that he would make the best Death personification due to how powerful he came and just destroyed imo (in my opinion) Comic Book's Gary Stu @ Superman. It gets taken out and made that Superman doesn't die. However for me he was the one that did it and it should've stayed that way at least in one timeline.
War - Video Game Realm - Metal Gear Solid - Solid Snake. He has seen plenty of War for those that have followed his timeline. War made him kill someone he considered a close friend @ Gray Fox or at least he thought so. War also made him kill his own father aka Big Boss. For those that never seen or heard of Solid Snake just look up the first cutscene he appears in Metal Gear Solid 4. I would say that monologue shows how much War has done to him.
Pestilence - Anime Realm - Inuyasha - Naraku. From what I know his name literally means Hell. He used his Demonic Energy/Essence to make many weaker demons and humans around him sick. He even killed one of his Incarnations with that ability of his. At one point he was one of my favorite villains of all time.
Famine - Real Realm - This Timeline - Wal. I decided to put myself in this slot, not one of the most popular Horsemen. I cringe and voice myself when I see someone waste food. It is one of the things I hate the most in this World. Not to sound so morbid/mean and take it with a pinch of salt/fantasy; if I had the power of Famine I would take away the food from those that waste it and make sure they suffer for thinking that they can just waste their own surplus. P.S - Brownie Points for the one that knows what character I am kinda/sorta cosplaying as.
Art by - Ting and Wal
Doomsday (c) DC Comics
Solid Snake (c) Konami
Naraku (c) Rumiko Takahashi
Wal (c) Wal...lol